Clinical trials and guidelines

Clinical trials (see also Clinical guidelines...)

UKI NETS is currently undertaking some multi-centre studies.  The following is for information only and does not represent the definitive version of the trial protocol.

  Sponsor Trial phase Trial design Target population Primary end pt No. pts
Lanreotide Autogel vs placebo in non-functioning gastroenteropancreatic NETS Ipsen Phase III Lanreotide autogel 120 mg vs placebo Non-functional Entero-pancreatic or Unknown primary PFS 200

NET01 – Chemotherapy in metastatic pancreatic NETS and NETS of unknown origin (NCRI adopted) (pdf) (20kb)

NET01 Newsletter January 2008 (pdf) (88kb)

Cambridge Randomised Phase II Cap-strep vs Cap-Cist Foregut, unknown primary,Progressing disease PFS 84

Further studies are planned involving the use of newer agents including RAD001, antiangiogenic agents, and radionucleotide therapy.

Clinical guidelines

Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (pdf) (250kb)